Stress and glucocorticoids impair retrieval of long-term spatial memory

Article Abstract:

Previous studies of animals and humans have shown that cognitive function is influenced by stress and glucocorticoids. A new study of rats investigates the effect of stress and glucocorticoids on long-term spatial memory. It is shown that rats which receive foot shocks 30 minutes before spatial task testing have an impaired performance, while those which receive footshocks 2 minutes or 4 hours before testing are not impaired. The impairment effects correspond to corticosterone levels at the time of testing.

Stress (Physiology), Neurobiology, Animal memory, Cognition in animals, Animal cognition

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Impaired auditory recognition of fear and anger following bilateral amygdala lesions

Article Abstract:

The amygdalar complex, a medial temporal lobe structure in the brain, is involved in the appraisal of danger and the emotion of fear. This was shown by a study involving a woman in her early 50s whose left and right amygdala were damaged following a series of stereotaxic operations. Impairment of social perception was observed after amygdala damage, with defective perception of visual signals of emotion emanating from the face, or more widely in the perception of emotion in all sensory modalities.

Auditory perception

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The amygdala and emotional memory

Article Abstract:

The storage of emotional memories in long-term memory appear to involve beta-adrenergic receptors and the amygdaloid complex in humans. This hypothesis was tested on two patients with Urbach-Wiethe disease, which damages the amygdaloid complex, using a beta-adrenergic blockage. The receptors and complex appear to only involve the storage of emotional memories since non-emotional memories were unaffected.

Physiological aspects, Memory, Beta adrenoceptors, Adrenergic beta receptors

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