Sunburnt fission yeast

Article Abstract:

Damaged DNA enters mitosis in all but two cases of mutants, as revealed by the genetic analysis of fission yeast. The mutants of one class prevent undamaged cells from arresting cells in G2, while those of the second class affect the normal functioning of the maturation promoting factor (MPF) by decreasing the minimal size cells must attain to be mitotic, and by destroying damaged DNA's ability to prevent entry into mitosis. The DNA damage in mammalian cells prevents the replication till the damage has been cured, indicating that DNA replication of fission yeast in controlled by gene products.

Genetic aspects, DNA damage

---

Creative blocks: cell-cycle checkpoints and feedback controls

Article Abstract:

Cells use DNA repair and spindle assembly as feedback controls before the cell division phase of the cell cycle. These feedback controls guarantee that DNA replication, repair and chromosome segregation are completed prior to division by stopping the cell cycle at one of three checkpoints until all three processes are finished. Research indicating that the breakdown of these feedback controls may contribute to carcinogenesis may point the way to more effective anti-cancer treatments.

Research, Cells (Biology), Growth, Cell cycle, Cells, Carcinogenesis

---

From molecular to modular cell biology

Article Abstract:

Cellular functions are undertaken by modules consisting of many species of interacting molecules. An understanding of the way modules work has relied on a combination of phenomenological analysis and molecular studies. It is likely that general principles governing the structure and behaviour of modules will be discovered with assistance from synthetic sciences, such as engineering and computer science.

Observations, Cell research, Cytological research

Similar abstracts:

• Abstracts: Arthropod phylogeny based on eight molecular loci and morphology. Sum of the arthropod parts
• Abstracts: The great gene shears story. Molecular medicine in development. The ultimate in atom manipulation
• Abstracts: On to molecular mechanisms. Theories on the brain. Strengths and weaknesses in memory
• Abstracts: Increased UV-B penetration in a lake owing to drought-induced acidification. Fractal stream chemistry and its implications for contaminant transport in catchments
• Abstracts: Concentration of plasma cholesterol in beef cows and calves, milk production and calf gain. Maternal performance of Hereford, Brangus, and reciprocal crossbred cows under semidesert conditions

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.