Transcribing diabetes

Article Abstract:

Maturity-onset diabetes of the young (MODY) is inherited in an autosomal dominant pattern, and develops before the age of 25. MODY is due to an insulin secretion impairment rather than an impairment in insulin action. Studies reveal that mutations at chromosomes 20q11.2-q13.1, 7p13 and 12q24 are responsible for MODY1, -2 and -3. The genes mutated in MODY3 and MODY1 encode hepatocyte nuclear factor (HNF)-1-alpha and HNF-4-alpha.

Physiological aspects, Gene mutations, Gene mutation, Diabetes, Diabetes mellitus

---

Tackling common disease

Article Abstract:

Research examining degrees to which defective variants of genes are responsible for predispositions to disease in people is presented. Particular attention is given to a critical account of identifications of genes associated with disease and to accompanying treatments discovered.

Health aspects, Diseases, Heredity

---

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

Article Abstract:

The localization of the type 1 diabetes susceptibility to the HLA-B and HLA-A genes belonging to class I of the major histocompatibility complex (MHC) is discussed. The MHC-class-I-mediated events contribute to the aetiology of type 1 diabetes.

Science & research, Research, Type 1 diabetes, Major histocompatibility complex, Human genome

Similar abstracts:

• Abstracts: Localization of apical epithelial determinants by the basolateral PDZ protein Scribble. Specificities of heparan sulphate proteoglycans in developmental processes
• Abstracts: The potential consequences of pollinator declines on the conservation of biodiversity and stability of food crop yields
• Abstracts: Database of molecular probes set to boost chemical genetics. More culls planned as Britain wrestles with foot-and-mouth
• Abstracts: The genetics of speciation. Correlation between male song repertoire, extra-pair paternity and offspring survival in the great reed warbler
• Abstracts: Representations of odours and odour mixtures visualized in the honeybee brain. Learning from a fly's memory

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.