Type ID unconventional myosin controls left-right asymmetry in Drosophila
Article Abstract:
The molecular nature of the determinants responsible for the invariant orientation of the left-right axis remains largely unknown and mutations producing a complete reversal of left-right asymmetry are instrumental for identifying mechanisms controlling handedness, yet only one such mutation is found in mice and snails. Thus, the conserved type ID unconventional myosin 31DF gene as a unique situs inversus locus in Drosophila is identified.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
A dynamic role for the mushroom bodies in promoting sleep in Drosophila
Article Abstract:
A screen of GAL4 lines in the fruitfly, Drosophila melanogaster is performed, expressing a temperature-sensitive synaptic blocker shibire in a range of discrete neural circuits and the amount of sleep at different temperatures is assayed. Three short-sleep lines were identified at the restrictive temperature with shared expression in the mushroom bodies, a neural locus central to learning and memory.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
An unconventional myosin in Drosophila reverses the default handedness in visceral organs
Article Abstract:
The internal organs of animals often have left-right asymmetry, and, though the formation of the anterior-posterior and dorsal-ventral axes in Drosophila is well understood, left-right asymmetry has not been extensively studied. It is found that the handedness of the embryonic gut and the adult gut and testes is reversed in viable and fertile homozygous Myo31DF mutants.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: A new canon. Retinoic acid coordinates somitogenesis and left-right patterning in vertebrate embryos. fgf8 mRNA decay establishes a gradient that couples axial elongation to patterning in the vertebrate embryo
- Abstracts: Transport news. Electronic measurement and control of spin transport in silicon. Silicon twists
- Abstracts: Rab3A is essential for mossy fibre long-term potentiation in the hippocampus. Synaptic scaling mediated by glial TNF-alpha
- Abstracts: A movement in four parts? Evolution and diversity of subduction zones controlled by slab width. The potential for giant tsunamigenic earthquakes in the northern Bay of Bengal
- Abstracts: Three-dimensional preservation of foot movements in Triassic theropod dinosaurs. An Early Jurassic jumping frog