Unmasking the killer's accomplice

Article Abstract:

Major histo-compatibility complex (MHC) class I molecules are polymorphic glycoproteins which are expressed on the surface of most cells in the body. They can be downregulated upon viral infection or in tumour cells, and the absence is sensed by natural killer (NK) cells. Natural killer cells monitor class I molecule expression using cell-surface receptors, and molecular cloning of the receptors show remarkable diversity. Lanier and colleagues have identified a complementary DNA encoding a molecule linked with one activating NK-cell receptor.

Observations, Major histocompatibility complex, Killer cells

---

TREM-1 amplifies inflammation and is a crucial mediator of septic shock

Article Abstract:

Research into the role of TREM-1 (the triggering receptor expressed on myeloid cells) is discussed. TREM-1 is an activating receptor of the immuno-globulin superfamily. TREM-1 amplifies inflammatory responses and could potentially be used in the treatment of septic shock.

Care and treatment, Inflammation, Inflammation mediators, Septic shock, Letter to the Editor

---

Key enzyme in leptin-induced anorexia

Article Abstract:

Research is presented describing the study of signal-transduction pathways in the regulation of food intake and the role of leptin in stimulating food requirements.

Anorexia nervosa, Leptin

Similar abstracts:

• Abstracts: Pissing their lives away: how the drug industry harms horses. New (veg) kids on the block: lettuce lunches
• Abstracts: Rationalization of the effects of mutations on peptide and protein aggregation rates. Mobile protein signals cell fate
• Abstracts: Continents ring the changes. Making composite continents. Dating of the oldest continental sediments from the Himalayan foreland basin
• Abstracts: Knocking out memory's door. Essential role of neocortical acetylcholine in spatial memory. Repression revisited
• Abstracts: The mystery of the sapropels. Formation of coastline features by large-scale instabilities induced by high-angle waves

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.