Variations on the theme of movement

Article Abstract:

Chemomechanical coupling necessary for kinesin-mediated cell motility may exist in more than one form. Laura Romberg and Ronald D. Vale examined how adenosine diphosphate (ADP) and nucleotide analogues affect motility and discovered that the microtubules slow down and separate from the cell surface when the ratio of ADP to adenosine triphosphate is less than one-to-one. Current theories as to how the actomyosin system functions may have to be revised in light of these findings.

Cells, Kinesin, Cell migration, Adenosine diphosphate

---

Control of CFTR chloride conductance by ATP levels through non-hydrolytic binding

Article Abstract:

Intracellular levels of adenosine triphosphate (ATP) must remain within normal limits for the sweat ducts to produce large amounts of cystic fibrosis transmembrane conductance regulator (CFTR) the genetic defect of which causes the disease cystic fibrosis. CFTR normally functions as a phosphorylation-induced small-conductance chloride channel. ATP's association with chloride channel activity through CFTR may prevent too great an expenditure of energy from injuring tissue.

Psychological aspects, Research, Cystic fibrosis, Chloride channels

---

Similar abstracts:

• Abstracts: Determination of the fold of the core protein of hepatitis B virus by electron cryomicroscopy. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding
• Abstracts: Electrical bursting of islet beta cells. ATP and chloride conductance. No electrostatic sense in snakes
• Abstracts: Structure of stratospheric intrusions into the troposphere. Contribution of stratospheric cooling to satellite-inferred tropospheric temperature trends
• Abstracts: Acceleration of the rate of nitrite oxidation by freezing in aqueous solution. Three-dimensional structure of photosystem II
• Abstracts: Vesicle assembly in microtubes. Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.