WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculaturea
Article Abstract:
A study reveals that macrophage WNT7b is a short-range paracrine signal required for WNT-pathway responses and programmed cell death in the vascular endothelial cells of the temporary hyaloid vessels of the developing eye in mice. These findings indicate that macrophages can use WNT ligands to influence cell-fate decisions, including cell death, in adjacent cells, and raise the possibility that they do so in many different cellular contexts.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
Neural crest origins of the neck and shoulder
Article Abstract:
The genes involved in the cellular modularity of the neck and shoulder skeleton are identified and a new method for determining skeletal homologies is proposed that is based on muscle attachments. The study has allowed tracing the whereabouts of the cleithrum, the major shoulder bone of extinct land vertebrate ancestors that seems to survive as the scapular spine in living mammals.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
Evolution of anatomy and gene control
Article Abstract:
The significance of the historical information in the development of anatomy, gene control and regulation and systems biology is discussed. The approach has proved to be extremely beneficial in describing the genetic features of old creatures.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2008
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: A model for p53-induced apoptosis. Life (and death) in a malignant tumour. Inactivation of hCDC4 can cause chromosomal instability
- Abstracts: Viral infection swithces non-plasmacytoid dendritic cells into high interferon producers
- Abstracts: A sharp lithosphere-asthenosphere boundary imaged beneath eastern North America. Boundary-layer mantle flow under the Dead Sea transform fault inferrred from seismic anisotrophy
- Abstracts: India makes waves over tsunami warning system. Purdue dogged by misconduct claims. India's nuclear debate hots up after tsunami floods reactor
- Abstracts: Gamma-band synchronization in visual cortex predicts speed of change detection. How sleep affects the developmental learning of bird song