Winning the drugs war
Article Abstract:
Scientific knowledge is critical to have better mechanisms and resources that will help in developing drugs and delivering them for fighting malaria and developing antimalarials. To ensure optimal use of new drugs and the availability of these new drugs to the patient, interactions across multiple disciplines, institutions and organizations should take place and it is necessary to have a coordinated action and dialogue between research and disease-control communities.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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A worthy adversary for malaria
Article Abstract:
An international collaboration of chemists, parasitologists, pharmacokineticists and toxicologists have used an old Chinese herbal medicine artemisinin as a template to develop a set of antimalarial drug compounds. It was seen that the resulting compounds formed using artemisinin were stable and showed parasitic killing properties when subjected to human strains of the malaria parasite.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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Identification of an anti-malarial synthetic trioxolane drug development candidate
Article Abstract:
The identification of a synthetic antimalarial trioxolane drug development candidate is described. It was seen that the 1,2,4-trioxolane drug development candidate, which was also known, as OZ277 or RBx-11160, showed structural simplicity, and was economically feasible, exhibited superior antimalarial activity and had an improved biopharmaceutical profile.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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