Conserved themes but novel activities in recombinases and topoisomerases
Article Abstract:
Type 1B topoisomerases and tyrosine recombinases have common structures and mechanisms that suggest a link between them. For instance, the mechanism of the two enzyme families involves the formation of a covalent 3' phosphotyrosine DNA-enzyme intermediate in a reaction independent of magnesium ions. The vaccinia enzyme consists of several motifs that are conserved among type 1B topoisomerases. The vaccinia enzyme also can resolve Holliday junctions and has a strict site selectivity, properties commonly observed in recombinases.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1998
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A novel mineral flotation process using Thiobacillus ferrooxidans
Article Abstract:
Thiobacillus ferrooxidans could be used to remove pyrite from a mineral solution. When added to five sulfide minerals in suspension, the bacterium reduced the floatability of pyrite from 90% or greater to less than 20%. The other four minerals were unaffected.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1999
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