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FSH directly regulates bone mass

Article Abstract:

Postmenopausal osteoporosis, a global public health problem, is attributed solely to estrogen levels, and although FSH levels rise sharply in parallel, a direct effect of FSH on the skeleton is never explored. After menopause, resorption significantly exceeds formation, and this imbalance results in net bone loss, while estrogen replacement slows postmenopausal bone loss, thus reducing the risk of fracture.

Author: Blair, Harry C., Zaidi, Mone, Moonga, Baljit S., Zallone, Alberta, Li Sun, Braun, Jonathan, Yuanzhen Peng, Zhiyuan Zhang, Ling-Ling Zhu, Papachristou, Dionysios J., Zaidi, Samir, Yaroslavskiy, Beatrice B., Hang Zhou, Sairam, M. Ram, Rajendra ,T. Kumar, Wei Bo, Cardoso-Landa, Luis, Schaffler, Mitchell B.
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
Science & research, Health aspects, Research, Bones, Risk factors, Bone density, Osteoporosis, Postmenopausal women

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TSH is a negative regulator of skeletal remodeling

Article Abstract:

Research has been conducted on thyroid stimulating hormone which promotes hormone secretion and thyroid follicle development. The role of this hormone in skeletal remodeling, osteoblastic bone formation and osteoclastic bone resorption has been investigated and discussed.

Author: Davies, Terry F., Abe, Etsuko, Marians, Russell C., Yu, Wanqin, Wu, Xue-Bin, Ando, Takao, Li, Yanan, Iqbal, Jameel, Eldeiry, Leslie, Rajendren, Gopalan, Blair, Harry C., Zaidi, Mone
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
Secretion, Osteoblasts, Bone development, Osteoclasis, Follicle-stimulating hormone, Thyrotropin

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TSH, the bone suppressing hormone

Article Abstract:

The author discusses the study of thyroid-stimulating hormone which plays an important role in bone homeostasis. The analysis of this hormone as a regulator of bone homeostasis is presented.

Author: Novack, Deborah Veis
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Hormones & Related Preparations, Hormone Preparations, Causes of, Hormones, Bone cells, Thyroid diseases, Homeostasis

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Subjects list: United States, Analysis, Physiological aspects, Genetic aspects, Genetic regulation, Cell research, Cytological research
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