Pneumococcal virulence factors: structure and function

Article Abstract:

This review elucidates the structural and functional aspects of the virulence factors in gram-positive bacteria exemplified by Streptococcus pneumoniae. The polysaccharide capsule and proteins are virulence factors and potential vaccine candidates as well. They exhibit highly alpha-helical domains and coil structure and aid in the adherence of pneumococcus to host cells.

Cell adhesion, Virulence (Microbiology), Cell surface antigens, Streptococcus pneumoniae, Cooperative binding (Biochemistry)

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Metabolic context and possible physiological themes of sigma (super)54 -dependent genes in Escherichia coli

Article Abstract:

The purpose of this article is to discuss on the role of sigma (super 54 in nitrogen assimilation. The functions of sigma (super)54 -dependent genes from Escherichia coli have been analyzed and the results indicate that that these genes have only metabolic themes that are possibly related.

Statistical Data Included, DNA, Escherichia coli, Metabolism, RNA polymerases, Microbiological research

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Biosynthesis of polyketides in heterologous hosts

Article Abstract:

Two heterologous hosts, Streptomyces coelicolor and Escherichia coli are employed to express polyketide synthases involved in the biosynthesis of polyketides. Polyketides are formed by repetitive condensation of 2- and 3-carbon acyl groups derived from coenzyme A thioesters.

Research, Microbiological synthesis, Biochemical genetics, Polyketides

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