Complementary analysis of peptide aggregation by NMR and time-resolved laser spectroscopy
Article Abstract:
The aggregation behavior of naphthyl-substituted beta(12-28) peptide analogues has been investigated using nuclear magnetic resonance and time-resolved laser spectroscopy. To this end, several beta(12-28) derivatives were synthesized in which the phenylalanine residues 19 and/or 20 were replaced with the nonnative amino acid, naphthylalanine to generate different peptides. The use of nuclear magnetic resonance and time-resolved laser spectroscopy was found to be effective for the complementary analysis of peptide aggregation due to their sensitivity to different ranges of molecular motion.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 1999
User Contributions:
Comment about this article or add new information about this topic:
Membrane curvature change induced by an antimicrobial peptide detected by (super 31)P exchange NMR
Article Abstract:
The influence of an antimicrobial peptide, protegrin-1 (PG-1) on the curvature and lateral diffusion coefficient (D(sub L)) of phosphocholine bilayers was investigated using one- (1-D) and two-dimensional (2-D) (super 31)P exchange NMR. The simulations of the 2D exchange spectra yielded quantitative reorientation-angle distributions were consistent with the bimodal distributions of the vesicles curvature and the effects of the peptide on the two types of lipid bilayers.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
Structure, topology, and dynamics of membrane peptides and proteins from solid-state NMR spectroscopy
Article Abstract:
Solid-state NMR spectroscopy is a powerful atomic-resolution probe that is used for determining the structure and dynamics of the membrane proteins. The combination of the solid-state NMR spectroscopy and the resonance assignment methods are important for elucidating the membrane-bound three-dimensional structure and dynamics and the lipid interaction of membrane proteins.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Discrimination between single Escherichia coli cells using time-resolved confocal spectroscopy. A Lattice-Gas Cellular Automaton to model diffusion in restricted geometries
- Abstracts: Dynamic intensity borrowing in porphyrin J-aggregates revealed by sub-5-fs spectroscopy. Excited state and ground state proton transfer rates of 3-Hydroxyflavone and its derivatives studied by Shpol'skii spectroscopy: the influence of redistribution of electron density
- Abstracts: Distribution of cations and vacancies in TaFe1.25Te3 studied by Mossbauer spectroscopy. Interpreting the oxidative catalytic activity in iron-substituted ferrierites using in situ Mossbauer spectroscopy
- Abstracts: Fractal nanochannels as the basis of the ionic transport in Agl-based glasses
- Abstracts: Competitive hydrolytic and elimination mechanisms in the urease catalyzed decomposition of urea. Theoretical calculations of refractive indices and optical effects in spectra of nitric acid and nitric acid monohydrate crystals