Spectroscopy and recognition chemistry of micelles from monoalkyl phosphoryl nucleosides

Article Abstract:

The preparation and properties of aqueous micelles derived from n-hexadecylphosphoryladenosine (C16-AMP), n-hexadecylphosphorylcytidine (C16-CMP) and n-hexadecylphosphoryluridine (C16-UMP) have been studied. Ultraviolet (UV) ultracentrifugation along with UV absorption and circular dichroism spectroscopic analysis have been undertaken. Results show the aggregation of the micelles is not affected by the chemical nature of the base. It was also observed that the complementary base binding is not more visible nor faster than binding in liposomes.

Analysis, Micelles, Nucleosides, Cooperative binding (Biochemistry)

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Imaging soft matter with the atomic force microscope: cubosomes and hexosomes

Article Abstract:

A study was conducted to analyze images of colloidal dispersions of liquid crystal phases of cubic and hexagonal structures in water using atomic force microscopy. The samples of cubosomes and hexosomes were imaged using the microscopy technique without additional purification. Experimental results indicated the effectiveness of atomic force microscopy in determining the morphology and structure of very soft matter in situ.

Research, Usage, Colloids, Atomic force microscopy, Liquid crystals

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