Tilt: Major factor in sterols' ordering capability in membranes
Article Abstract:
Extensive atomistic simulations are used to show that the single measurable parameter, the sterol tilt, can be used to determine a sterol's capability to induce order and to modify membrane properties. The smaller the tilt, the stronger was the ordering ability of a given sterol. This method differentiates the many sterols and therefore facilitates studies to find sterol molecules comparable to cholesterol in promoting the formation of highly ordered lipid rafts.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
Relating the organization of the molecular tilt azimuth to lateral-force images in monolayers transferred to solid substrates
Article Abstract:
A study was conducted to analyze the molecular tilt azimuth in domains of a condensed phase in monolayers of glcyerol esters at the air/water interface. The molecular tilt azimuth supported a regular star texture. In addition, there were regular patterns in images of monolayers on mica. Experimental results indicated that domains transferred to mica do not support the structure they had on the water surface.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 1998
User Contributions:
Comment about this article or add new information about this topic:
Replacing the cholesterol hydroxyl group with the ketone group facilitates sterol flip-flop and promotes membrane fluidity
Article Abstract:
The effects of substitution of hydroxyl group with the ketone group in cholesterol to produce ketosterone are investigated. The unstable positioning of the ketosterone at the membrane-water interface gives rise to flip-flop transitions, which decrease the polar interactions at the interface allowing ketosterone to penetrate from the hydrocarbon region of the membrane.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2008
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Excess enthalpies of mixing in phospholipid-additive membranes. Sensitivity of microarray oligonucleotide probes: Variability and effect of base composition
- Abstracts: Transient solidlike behavior near the cylinder/disorder transition in block copolymer solutions. Ion gels by self-assembly of a triblock copolymer in an ionic liquid
- Abstracts: Evaluation of Hofmeister effects on the kinetic stability of proteins. Calculation of hydration effects in the binding of anionic ligands to basic proteins
- Abstracts: Molecular recognition through H-bonding in micelles formed by dioctylphosphatidyl nucleosides. Probing the influence of X-rays on aqueous copper solutions using time-resolved in situ combined video/X-ray absorption near-edge/ultraviolet-visible spectroscopy
- Abstracts: Multiply charged redox-active oligomers in the gas phase: electrolytic electrospray ionization mass spectrometry of metallocenes