Metal complexes as enzyme inhibitors
Article Abstract:
Metal complexes that bind to an enzyme's active site could be used to inhibit the enzyme if excess enzymatic activity is causing disease. However, the metal complex must be specific to that enzyme, must be stable, non-toxic, and bioavailable, and must produce no compensatory effects.
Publisher: American Chemical Society
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 1999
Coordination compounds, Enzyme inhibitors
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 1999
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Metal complexes for therapy and diagnosis of drug resistance
Article Abstract:
Inorganic metal complexes may be useful in treating drug-resistant malaria and leishmaniasis. Technetium-sestamibi can be used to identify cancer patients who have a drug-resistant tumor.
Publisher: American Chemical Society
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 1999
Drug therapy, Malaria, Drug resistance
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 1999
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Subjects list: Health aspects, Research, Inorganic compounds
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