How T cells count
Article Abstract:
Immunologist Antonella Viola has discovered that T cells activate when a certain quantity of T cell receptors (TCRs) are engaged by a foreign peptide major histocompatibility complex (MHC). The low affinity of TCR interactions with ligands is essential to the 'counting' mechanism.
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1996
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T Cells and Dendritic Cells Get Intimate
Article Abstract:
Dendritic cells and T cells must interact to activate the body's immune response against pathogens. When the dendritic cells are immature they cannot activate the T cells, but when they mature the dendritic cells move to lymphoid organs and are then able to activate the T cells.
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1999
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