The association of ancestral longevity with successful aging
Article Abstract:
As the more capricious causes of death, such as infection and life style factors, come under control, more people will reach a relatively predictable and genetically determined age. If so, the hereditary factors determining the length of life may also predict psychological vitality in old age. The genetic contributions to a long life were first described in 1934, and our understanding of the contribution of ancestral longevity has not progressed much since then. It is supposed that the causes of longevity and successful aging result from more than one gene (polygenic). Methodological problems with longevity studies include the problems of memory inherent in retrospective studies, and the discouraging effect on prospective studies of subjects outliving the researchers, as is the case with the prospective Study of Adult Development begun at Harvard in 1938, and lasting for 50 years. The men were recruited at Harvard University when they were between 18 and 20 years old. Their high socioeconomic status ensured good health care and a reduced likelihood of death from hazardous occupations. One hundred eighty-eight of the original sample of 204 were surveyed to determine whether ancestral longevity was associated with psychosocial vigor and satisfaction in late mid-life. It was found that those with long-lived ancestors tended to have better health and survival rates to age 68, although the relationship was not statistically significant. It is possible that as these men reach their 80s the association between ancestral longevity and more successful aging will become more pronounced. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: Journals of Gerontology
Subject: Seniors
ISSN: 0022-1422
Year: 1991
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A correlation between DNA repair capacity and longevity in adult Drosophila melanogaster
Article Abstract:
Somatic mutation theories relate aging to the accumulation of somatic cell mutations, which could be counteracted by DNA repairs. To verify whether lowered DNA repair capacity would lead to accelerated aging and a shorter lifespan, three temperature- and mutagen-sensitive Drosophila melanogaster strains were exposed to methyl methanesulfate (MMS). All strains had substantially shorter life spans, regardless of exposure, at the restricted temperature. Exposure during development to low doses of MMS further reduced life span.
Publication Name: Journals of Gerontology
Subject: Seniors
ISSN: 0022-1422
Year: 1993
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Physical measurements in an elderly black population: knee height as the dominant indicator of stature
Article Abstract:
Stature among the elderly Black population was assessed using knee height, gender, weight, and age as variables. The study included a total population of 119, 21 males and 98 females, with an age range of 60-102 years old and physical measurements were taken in the sitting position. The study showed, in descending order, that kneeheight, gender, and weight were significant in the estimation of stature while age was not.
Publication Name: Journals of Gerontology
Subject: Seniors
ISSN: 0022-1422
Year: 1993
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