Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts

Article Abstract:

The apical localization of Inscuteable in Drosophila requires Bazooka, a protein with a PDZ domain. Bazooka localizes with Inscuteable in neuroblasts, binding to the Inscuteable localization domain. Direct biding to Bazooka is thought to mediate the asymmetric localization of Inscuteable.

Nervous system

---

Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon

Article Abstract:

The article describes a biochemical link between the cell cycle and the asymmetric protein localization machinery and indicates that Polo can inhibit progenitor self-renewal by regulation of localization and function of Numb.

Analysis, Cell cycle

---

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl

Article Abstract:

The Drosophila Par protein complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. Discusses the research, accompanied by cellular photographs.

Protein research

Similar abstracts:

• Abstracts: Variation and consistency of female preferences for simulated courtship songs in Drosophila virilis. Behavioural isolation between two closely related Hawaiian Drosophila species: the role of courtship
• Abstracts: Uniform discrimination of pattern orientation by honeybees. Worker nutrition and division of labor in honeybees
• Abstracts: Swallowing ornamental asymmetry. Mutual sexual selection in a monogamous seabird. Aerodynamics and the evolution of long tails in birds
• Abstracts: Hydrous olivine unable to account for conductivity anomaly at the top of the asthenosphere
• Abstracts: A trehalose metabolic enzyme controls inflorescence architecture in maize. Genetics of gene expression surveyed in maize, mouse and man

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.