Abstracts - faqs.org

Abstracts

Zoology and wildlife conservation

Search abstracts:
Abstracts » Zoology and wildlife conservation

Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

Article Abstract:

A small inversion within chromosome 2p has resulted in the formation of a fusion gene comprising proteins of the echinoderm microtubule-associated protein-like 4 (EML4) gene and the anaplastic lymphoma kinase (ALK) gene in non-small-cell lung cancer (NSCLC) cells. The results have shown that a subset of NSCLC proteins have expressed a transforming fusion kinase, which might be a promising candidate for a therapeutic target as well as for a diagnostic molecular marker in NSCLC.

Author: Aburatani, Hiroyuki, Soda, Manabu, Young Lim Choi, Enomoto, Munehiro, Takada, Shuji, Yamashita, Yoshihiro, Ishikawa, Shunpei, Fujiwara, Shin-ichiro, Watanabe, Hideki, Kurashina; Hatanaka, Hisashi, Bando, Masashi, Ohno, Shoji, Ishikawa, Yuichi, Niki, Toshiro, Sohara, Yasunori, Sugiyama, Yukihiko, Mano, Hiroyuki
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
Japan, Analysis, Genetic aspects, Polymerase chain reaction, Cell proliferation, Lung cancer, Small cell, Small cell lung cancer

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

A microtubule-binding myosin required for nuclear anchoring and spindle assembly

Article Abstract:

The Xenopus laevis myosin-10 (Myo10) that associates with microtubules in vitro and in vivo, and is concentrated at the point where the meiotic spindle contacts the F-actin-rich cortex is presented. The results as well as demonstrations showing that other unconventional myosins can associate with microtubules indirectly or directly suggest that myosin has a novel and critically important role during meiosis in integrating the F-actin and microtubule cytoskeletons.

Author: Weber, Kari L., Sokac, Anna M., Berg, Jonathan S., Cheney, Richard E., Bement, William M.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
Xenopus, Spindle (Cell division), Spindle (Cytoplasm), Myosin

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

Fission yeast mod5p regulates polarized growth through anchoring of tea 1p at cell tips

Article Abstract:

The tea1p and mod5p act in a positive-feedback loop in the microtubule-mediated regulation of cell polarity. Its various consequences are detailed.

Author: Sawin, Kenneth E., Snaith, Hillary A.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
United States

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Subjects list: Research, Microtubules
Similar abstracts:
  • Abstracts: Identification of Vangl2 and Scrb1 as planar polarity genes in mammals. Adaptation of core mechanisms to generate cell polarity
  • Abstracts: Coherent quantum control of two-photon transitions by a femtosecond laser pulse. Discretizing light behaviour in linear and nonlinear waveguide lattices
  • Abstracts: Genetic modification of heterochromatic association and nuclear organization in Drosophila. Versatile assembler
  • Abstracts: Production and evolution of light elements in active star-forming regions. Dodecahedral space topology as an explanation for weak wide-angle temperature correlations in the cosmic microwave background
  • Abstracts: Functional impact of syntaxin on gating of N-type and Q-type calcium channels. The role of neuronal identity in synaptic competition
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2023 Advameg, Inc.