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Adult cardiac stem cells are multipotent and support myocardial regeneration

Article Abstract:

Research demonstrates that a subpopulation of replicating myocytes in adult heart possess properties of cardiac stem cells. Data indicate that they self-renew, clonogenic, and multipotent and produce myocytes, smooth muscle, and endothelial cells. These stem cells when injected into an ischemic heart are able to reconstitute well-differentiated myocardium.

Author: Anversa, Piero, Chimenti, Stefano, Nadal-Ginard, Bernardo, Beltrami, Antonio P., Urbanek, Konrad, Kajstura, Jan, Leri, Annarosa, Musso, Ezio, Barlucchi, Laura, Torella, Daniele, Baker, Mathue, Limana, Federica, Kasahara, Hideko, Rota, Marcello
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
Physiological aspects, Growth, Cell differentiation, Stem cells, Heart muscle, Myocardium, Heart cells, Company growth

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Canadian stem cells scientists take the prize

Article Abstract:

The recipients of the Lasker Award for Basic Medical Research in 2005 are Ernest A. McCulloch and James E. Till. The landmark studies of McCulloch and Till in the 1960s defined the hallmark properties of stem cells, the ability to self-renew and differentiate.

Author: Sharkis, Saul J.
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2005
Achievements and awards, Stem cell research, McCulloch, Ernest A., Till, James E.

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Subjects list: United States
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