Arginine methylation of STAT1 modulates IFN(alpha)/beta-induced transcription

Article Abstract:

Research has been conducted on the interferon transcriptional induction requiring tyrosine and serine phosphorylation of signal transducers and activators of transcription (STAT) factors. The arginine methylation of STAT1 by protein arginine methyl-transferase as a requirement for the IFN(alpha)/beta-induced transcription has been carried out and the results are reported.

Proteins, Phosphorylation, Arginine, Serine, Methylation, Tyrosine

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Gene switching by metabolic enzymes- how did you get on the invitation list?

Article Abstract:

The author discusses the study on histone gene expression in mammalian cells. The topics of interest include the role of enzyme glyceraldehyde-3-phosphate dehydrogenase in the OCA-S coactivator complex, and redox dependence on in vitro transcription of histone genes.

Enzymes, Other Basic Organic Chemical Manufacturing, Genetic aspects, Histones, Phosphates, Metabolism, Gene expression, Oxidoreductases, Oxidation-reduction reaction, Oxidation-reduction reactions, Aldehydes

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