Bacterial senescence: stasis results in increased and differential oxidation of cytoplasmic proteins leading to developmental induction of the heat shock regulon

Article Abstract:

Bacteria, along with all other life forms, may become more fragile as it ages through oxidative sensitivity of TCA cycle enzymes. Levels of oxidized proteins has been correlated to the age of Escherichia-coli culture, and this increase is higher in cells that lack the global regulators OxyR and sigma(super)s. Protein oxidation signals induction of the heat shock regulon.

Bacteria, Proteins, Cells, Cell aging

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Novel Helicobacter pylori alpha1,2-fucosyltransferase, a key enzyme in the synthesis of Lewis antigens

Article Abstract:

Research was conducted to express, characterize and compare alpha1,2-fucosyltransferase of Helicobacter pylori with the mammalian type. Results show the enzyme can be overproduced in Escherichia coli, is involved in the synthesis of Lewis antigens of lipopolysaccharide and differs from mammalian enzyme in several properties.

Canada, Analysis, Usage, Escherichia coli, Enzymes, Microbiological synthesis, Endotoxins, Bacterial cell walls, Cell membranes, Enzyme regulation

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