Connecting cancer to the asymmetric division of stem cells

Article Abstract:

A study demonstration that the cell-fate determinant Brain Tumor (Brat) suppresses self-renewal in one of the daughter cells that arises from the asymmetric division of a neural stem cell is presented. The findings suggest a mechanism by which loss of polarity in stem cells might lead to tumorigenesis.

United States, Brain tumors, Brain tumours, Stem cell research

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Bacterial mitotic machineries

Article Abstract:

Fundamental new insight into the molecular mechanisms behind plasmid and chromosome segregation in prokaryotic cells is reviewed. A study is conducted to show how prokaryotic actin homologs form mitotic machineries that segregate DNA before cell division.

Cells (Biology), Plasmids, Cells

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Coordination of cell division and chromosome segregation by a nucleoid occlusion protein in Bacillus subtilis

Article Abstract:

The identification of a specific effector of nucleoid occlusion in Bacillus subtilis is discussed. YyaA contributes to the correct placement of the division site and reduces the risk of chromosome damage during division.

Bacillus subtilis

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