Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins

Article Abstract:

A cooperative interaction between the DNA binding domains of the myocyte enhancer factor-2 (MEF2) and the myogenic basic helix-loop-helix (bHLH) proteins increases muscle gene expression. MEF2 binds to the E box target regions of bHLH. The stimulation of gene expression in fibroblasts requires a transactivation domain in either MEF2 or BHLH. The probable mechanisms of muscle gene activation are discussed.

Genetic aspects, Muscles, Gene expression, Cooperative binding (Biochemistry)

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A unified nomenclature system for the Drosophila odorant receptors

Article Abstract:

This article reports on the odorant receptor genes of Drosophila coding transmembrane domain receptor proteins that are expressed in the olfactory receptor neurons. A total of 60 odorant receptors are currently identified.

United States, Drosophila, Neurons, Cell receptors

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