Abstracts - faqs.org

Abstracts

Biological sciences

Search abstracts:
Abstracts » Biological sciences

Divergence of melanocortin pathways in the control of food intake and energy expenditure

Article Abstract:

A loxP-modified, null melanocortin-4-receptors (MC4R) allele that can be reactivated by Cre-recombinanse is generated to identify the functionality relevant sites of MC4R expression. The findings reveal that MC4Rs in the paraventricular nucleus of the hypothalamus and/or the amygdala control food intake but that MC4Rs elsewhere control energy expenditure.

Author: Lowell, Bradford B., Boss, Olivier, Elmquist, Joel K., Williams, Todd, Balthasar, Nina, Dalgaard, Louise T., Mountjoy, Kathleen, Kishi, Toshiro, Lee, Charlotte E., Jia Yu, Funahashi, Hisayuki, Ferreira, Manuel, Tang, Vinsee, McGovern, Robert A., Kenny, Christopher D., Christiansen, Lauryn M., Edelstein, Elizabeth, Aschkenasi, Carl, Chen-yu Zhang
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2005
Energy metabolism, Bioenergetics, Hypothalamus, Amygdala (Brain)

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1 alpha null mice

Article Abstract:

PGC-alpha is a coactivator of nuclear receptors and other transcription factors that regulates several metabolic processes, including mitochondrial biogenesis and respiration, hepatic gluconeogenesis, and muscle fiber-type switching. The central role for PGC-1 alpha in the control of energy metabolism is illustrated.

Author: Lowell, Bradford B., Spiegelman, Bruce M., Cooper, Marcus P., Mootha, Vamsi K., Shulman, Gerald I., Wu, Zhidan, St-Pierre, Julie, Lin, Jiandie, Lindenberg, Katrin S., Fan, Melina C., Zavacki, Ann Marie, Rohas, Lindsay M., Jager, Sibylle, Zhang, Chen-yu, Krainc, Dimitri, Cinti, Saverio, Tarr, Paul T., Wu, Pei-Hsuan
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2004
Genetic transcription, Transcription (Genetics), Origin of life, Gluconeogenesis

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Subjects list: Research
Similar abstracts:
  • Abstracts: Independent occurrences of multiple repeats in the control region of mitochondrial DNA of white-tailed deer. Partial cytochrome b sequences for six hymenoptera of the Eastern United States
  • Abstracts: Differential timing and control of noncrossover and crossover recombination during meiosis. The control of mammalian DNA replication: a brief history of space and timing
  • Abstracts: A spatial map of olfactory receptor expression in the Drosophila antenna. Two-photon calcium imaging reveals an odor-evoked map of activity in the fly brain
  • Abstracts: Cdc13 deliveres separate complexes to the telomere for end protection and replication. Switching and signaling at the telomere
  • Abstracts: A pathway for association of receptors, adaptors, and actin during endocytic internalization. Transgenic expression of syndecan-1 uncoveres a physiological control of feeding behavior by syndecan-3
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2025 Advameg, Inc.