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Heterotrimeric G protein signaling: Getting inside the cell

Article Abstract:

Heterotrimeric G protein alpha subunit functions at the endosome to stimulate a phosphatidylinositol 3-kinase to help yeast respond to mating pheromones. The identification of intracellular G protein effector and establishing its physiological significance in signaling through genetic tests has helped in understanding heterotrimeric G protein signaling.

Author: Koelle, Michael R.
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
Science & research, Research, Eukaryotes, Cell membranes, G proteins, Structure, Transduction, Transduction (Genetics)

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Endocytosis and signaling: an inseparable partership

Article Abstract:

The authors review publications on the endocytosis through the clathrin-coated pits. The topics of interest include signaling from endosomes and its relevance, endocytic pathway as a switch-off for receptor signaling and signaling activation by endocytosis.

Author: Di Fiore, Pier Paolo, De Camilli, Pietro
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
Italy, United States, Statistical Data Included, Cell research, Cytological research, Endocytosis, Clathrin

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Subjects list: Analysis, Physiological aspects, Genetic aspects
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