F1 - ATPase is a highly efficient molecular motor that rotates with discrete 120 degree steps

Article Abstract:

The study investigated the rotation of the gamma-attached actin at low adenosine triphosphate (ATP) concentrations. This was done by fixing a subcomplex of the protruding portion of the ATP synthase onto a surface-bound bead with ten histidines linked to the amino terminus of the beta subunit. Rotation was observed using a fluorescently labeled actin filament attached to the gamma subunit. Results found that rotation of the actin was resolved into discrete 120 degree-steps with occasional back steps. A high thermodynamic efficiency was also noted in the process.

Models, Adenosine triphosphate, ATP, Adenosine triphosphatase, Catalysis

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mut-7 of C. elegans, required for transposon silencing and RNA interference is a homolog of Werner syndrome helicase and RNaseD

Article Abstract:

A model in which MUT-7, guided by transposon-derived dsRNA, represses transposition by degrading transposon-specific messengers and prevents thereby transposase production and transposition, is proposed. It appears that NRAi may work by dsRNA-directed enzymatic RNA degradation. One Tc1 silenced strain of C. elegans has been has been mutagenized. Mutants in which Tc1 was activated in the germline were isolated.

Netherlands, Statistical Data Included, Physiological aspects, Cytochemistry, RNA, Homology (Biology), Caenorhabditis elegans, Transposons

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