Functional proteomics reveals the biochemical niche of C.elegans DCR-1 in multiple small-RNA-medicated pathways

Article Abstract:

A study was conducted to learn how C.elegans Dicer, DCR-1, functions in multiple distinct silencing mechanisms where a mass-spectrometry-based proteomics approach was used to identify DCR-1-interacting proteins. The findings provide a first glimpse at the complex biochemical nice of Dicer and suggests that competition exists between DCR-1-mediated small-RNA path-ways.

United States, Japan, Biological Product (except Diagnostic) Manufacturing, Drugs, Deoxyribonucleic Acid, DNA, Gene silencing, RNA interference

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A panoramic view of yeast noncoding RNA processing

Article Abstract:

Research has been conducted on yeast functional proteomics and genomics. The authors discuss the data revealing yeast noncoding RNA processing, and report that uncharacterized yeast proteins are involved in noncoding RNA biogenesis.

Canada, Analysis, Physiological aspects, Genetic aspects, Proteins, Gene expression, RNA, Yeast fungi, Yeasts (Fungi), Cell research, Cytological research, Origin of life, Proteomics, Genomics

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