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Genomic targets of the human c-Myc protein

Article Abstract:

Research has been conducted on transcription factor Myc which regulates downstream cellular responses. The authors have investigated a large-scale sceen for genomic Myc-binding sites in human cells via the use of bioinformatics, and they report that there is high regulatory and biological diversity among Myc-target genes.

Author: Frank, Scott R., Schroeder, Marianne, Amati, Bruno, Fernandez, Paula C., Wang, Luquan, Liu, Suxing, Greene, Jonathan, Cocito, Andrea
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
Italy, Biological Product (except Diagnostic) Manufacturing, Drugs, Deoxyribonucleic Acid, Usage, DNA, Genetic regulation, Genomes, Computational biology

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Werner syndrome protein limits MYC-induced cellular senescence

Article Abstract:

Research has been conducted on MYC oncoproteins. The authors report that MYC overexpression leads to transcription stimulation of the human Werner syndrome gene.

Author: Oshima, Junko, Dalla-Favera, Riccardo, Fernandez, Paula, Amati, Bruno, Russell, David W., Grandori, Carla, Wu, Kou-Juey, Ngouenet, Celine, Grim, Jonathan, Clurman, Bruce E., Moser, Michael J., Swisshelm, Karen, Frank, Scott, Monnat, Raymond J., Jr.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
Causes of, Growth, Cancer cells, Oncogenes, Company growth, Werner syndrome

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Subjects list: United States, Analysis, Physiological aspects, Genetic aspects, Proteins, Gene expression, Genetic transcription, Transcription (Genetics), Genetic research
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