Isolation and characterization of temperate bacteriophages of Clostridium difficile

Article Abstract:

The aim of the study was to isolate and characterize bacteriophages specific for Clostridium difficile as a preliminary to assessing their potential as novel therapeutic agents. Superinfection and DNA analyses revealed relatedness between the phages, while partial sequencing of PhiC2 showed nucleotide homology to the sequenced C. difficile strain CD630.

Bacteriophages

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Quantification of cell proliferation and alpha-toxin gene expression of Clostridium perfringens in the development of necrotic enteritis in broiler chickens

Article Abstract:

The relationship between cell proliferation and alpha-toxin gene expression of Clostridium perfringens in the development of necrotic enteritis (NE) is examined. Non-bacitracin-treated birds have shown typical NE symptoms and reduced growth performance along with increased Clostridium perfringens proliferation and alpha-toxin gene expression.

Analysis, Physiological aspects, Polymerase chain reaction, Cell proliferation, Enterocolitis, Pseudomembranous, Necrotizing enterocolitis, Enterocolitis, Neonatal necrotizing

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