Molecules into cells: Specifying spatial architecture

Article Abstract:

Some conceptual issues in the genesis of spatial architecture, including how molecules find their proper location in cell space, the origins of supramolecular order, the role of the genes, cell morphology, the continuity of cells, and the inheritance of order are addressed. This leads to the conclusion that cell represents a fundamental unit of biological organization, a state of matter that is not wholly reducible to its molecular constituents.

Research and Development in the Physical, Engineering, and Life Sciences, Cellular Biology, Morphology (Biology), Cytology, Morphology, Molecular microbiology

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Phenotypic and transcriptomic analyses demonstrate interactions between the transcriptional regulators CtsR and sigma B in Listeria monocytogenes

Article Abstract:

Three Listeria monocytogenes strains are created in order to examine the contributions of the negative regulator (CtsR) to stress response and virulence and also to explore interactions between CtsR and the stress-responsive alternative sigma factor ([[sigma].sup.B]). The results have shown that interactions between CstR and [[sigma].sub.B] has played a key role in Lysteria monocytogenes stress resistance and virulence.

Genetic transcription, Transcription (Genetics), Listeria monocytogenes

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Alternative sigma factors and their roles in bacterial virulence

Article Abstract:

Review focusing on both direct and indirect roles of selective alternative sigma factors in regulating virulence of bacterial pathogenes of plants and animals is presented. A comparison of homologous sigma factor functions among different bacterial genera reveals that the role of sigma factors vary greatly among bacterial species, even for closely related species such as E. coli and S. enterica serovar Typhimurium.

RNA polymerases, Virulence (Microbiology)

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