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NUC-1, a Caenorhabditis elegans DNase II homolog, functions in an intermediate step of DNA degradation during apoptosis

Article Abstract:

NUC-1 is a Caenorhabditis elegans DNase II homolog that acts in an intermediate step of DNA degradation in apoptosis. The C. elegans gene, nuc-1, was cloned and TUNEL technique was used to measure DNA degradation in nuc-1 and other mutants in which apoptosis is defective.

Author: Wu, Yi-Chun, Stanfield, Gillian M., Horvitz, H. Robert
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2000
Cell death, Enzymes

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Nuclear reorganization and homologous chromosome pairing during meiotic prophase require C. elegans chk-2

Article Abstract:

Meiotic prophase nuclear reorganization and homologous chromosome pairing have been found, during analysis of a gene defined by pairing-defective mutants, to require Caenorhabditis elegans chk-2. A first molecular link between two landmark meiotic events has been found.

Author: Villeneuve, Anne M., MacQueen, Amy J.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2001
Statistical Data Included, Meiosis

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The C. elegans protein CEH-30 protects male-specific neurons from apoptosis independently of the Bcl-2 homolog CED-9

Article Abstract:

The importance of the Caenorhabditis elegans Bar protein CEH-30 in protecting the male-specific neurons from apoptosis is explained.

Author: Horvitz, H. Robert, Schwartz, Hillel T.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
Science & research, Neurons, Apoptosis

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Subjects list: Research, United States, Physiological aspects, Genetic aspects, DNA damage, Cytochemistry, Caenorhabditis elegans
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