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Opportunities and challenges in the development of kinase inhibitor therapy for cancer

Article Abstract:

Summarization of the growing evidence that kinase inhibitor therapy works consistently and reliably against cancers in which the kinase drug target is constitutively activated by gene mutation is presented. Perspective on future drug discovery and clinical trial design programs in molecularly targeted therapy can be modified based on present clinical experience with kinase inhibitors is presented.

Author: Sawyers, Charles L.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
Care and treatment, Usage, Causes of, Gene mutations, Gene mutation, Cancer, Cancer genetics

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Translational disconnect

Article Abstract:

New strategies that should be adopted to ensure the flow of adequate funds for the research and development of bioscience and pharmaceuticals are discussed. Governmental support, angel investing and appropriate financial management is few of the most necessary steps to be taken to overcome the problem.

Author: Frank, Frederick, Walton, Alan
Publisher: Scientist Inc.
Publication Name: The Scientist
Subject: Biological sciences
ISSN: 0890-3670
Year: 2008
United States, Government expenditures, Government finance, Pharmacology, Experimental, Pharmacological research

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Bioprospecting for microbial endophytes and their natural products

Article Abstract:

The study reveals potential prospects of finding new drugs that may be effective candidates for treating newly developing diseases in humans, plants, and animals.

Author: Strobel, Gary, Daisy, Bryn
Publisher: American Society for Microbiology
Publication Name: Microbiology and Molecular Biology Reviews
Subject: Biological sciences
ISSN: 1092-2172
Year: 2003
Endophytes

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Subjects list: Research, Drugs
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