RNA-binding protein conserved in both microtubule- and microfilament-based RNA localization

Article Abstract:

Vg1 RNA-binding protein (RBP) play a direct role in vegetal localization and this implies the existence of a general mechanism for mRNA targeting. Five RNa binding motifs were found in purified and cloned Vg1 RBPs. The experiments are explained in detail. Vg1 RBP is homologous to ZBP-1, a protein associated with mRNA targeting in fibroblasts. There are, however, important differences also.

RNA, Cytoplasmic filaments

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The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells

Article Abstract:

Research has been conducted on ch-TOG/XMAP215 proteins which bind to microtubules. The authors report that human somatic cells are more important for organizing spindle poles and less important for stabilizing spindle microtubules.

United Kingdom, Somatic cells

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A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo

Article Abstract:

Research has been conducted on protein phosphatase 2A. The authors describe the study of the phylogenetically conserved mechanism generating phospho-serine/threonine-specific protein phosphatase 2A in vivo.

Austria, Physiological aspects, Phylogeny, Phosphatases, Serine, Origin of life, Threonine

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