Abstracts - faqs.org

Abstracts

Biological sciences

Search abstracts:
Abstracts » Biological sciences

Real-time observation of RecA filament dynamics with single monomer resolution

Article Abstract:

Single-molecule fluorescence assays and hidden Markov modeling are used to show the most direct evidence that a RecA filament grows and shrinks primarily one monomer at a time and only at the extremities. Results support the proposal that a sufficient role for the RecA-loading machineries in helping RecA replace single-stranded deoxyribonucleic acid (DNA) binding protein (SSB) is to provide a nucleation cluster-like structure to initiate RecA-filament extension.

Author: Rasnik, Ivan, McKinney, Sean A., Chirlmin Joo, Nakamura, Muneaki, Sua Myong, Taekjip Ha
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
United States, Genetic recombination

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

Article Abstract:

Human Rad51, a structural homolog of Escherichia coli RecA, mediates homology recognition and initiates strand exchange. However, additional proteins are needed in extensive heteroduplex formation in higher organisms. This was gleaned from an investigation of the biochemical properties of hRad51 in vitro. It was also found that the binding of hRad51 to dsDNA facilitates end-to-end joining by DNA ligase.

Author: Baumann, Peter, West, Stephen C., Benson, Fiona E.
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1996
Genetic aspects, Testis, Homology (Biology)

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Are mouse telomeres going to Pot?

Article Abstract:

The roles of murine Pot1 homologs are examined and the way in which the cells protect their chromosome ends from DNA-repair activities are described. The computational analyses of transcript sequences and microarray profiling of splicing have provided a detailed understanding of the extent and complexity of AS in different cells and tissues.

Author: Baumann, Peter
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
Telomeres, Genetic research

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Subjects list: Research, DNA repair, DNA binding proteins
Similar abstracts:
  • Abstracts: Genetic position of Valencia (Spain) in the Mediterranean basic according to Alu insertions. Polymorphic Alu insertions in six Brazilian African-derived populations
  • Abstracts: Germline missense mutations affecting KRAS isoform B are associated with a severe noonan syndrome phenotype. CEP290 mutations are frequently identified in the oculo-renal form of Joubert syndrome-related disorders
  • Abstracts: High temporal but low spatial heterogeneity of bacterioplankton in the Chesapeake Bay. Stratified communities of active archaea in deep marine subsurface sediments
  • Abstracts: Tellurite resistance and reduction by obligately aerobic photosynthetic bacteria. Anaerobic respiration on tellurate and other metalloids in bacteria from hydrothermal vent fields in the eastern Pacific Ocean
  • Abstracts: OPA1 controls apoptosis cristae remodeling independently from mitochondrial fusion. OPA1 and PARL keep a lid on apoptosis
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2025 Advameg, Inc.