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Recent advances in IL-6 related to autoimmunity

Article Abstract:

Interleukin-6 (IL-6), a multifunctional cytokine that induces differentiation of B cells to antibody-producing plasma cells has promoted the development of T-helper 17 cells that affect the pathogenesis of autoimmune diseases. The analysis of IL-6 has suggested that IL-6 might be a vital factor to polarize, to increase T helper cells (Th17) and to inhibit regulatory T cells, leading to autoimmunity.

Publisher: Scientist Inc.
Publication Name: The Scientist
Subject: Biological sciences
ISSN: 0890-3670
Year: 2007
Interleukin-6

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The cause: A balanced attack

Article Abstract:

The discovery and characterization of the regulatory pathways might lead to the discovery of new drugs and cell therapies for autoimmune diseases. Scientists studying autoimmunity are trying to understand the homeostasis in the immune system, including balance within and between central and peripheral tolerance.

Author: Bluestone, Jeffrey A.
Publisher: Scientist Inc.
Publication Name: The Scientist
Subject: Biological sciences
ISSN: 0890-3670
Year: 2007
Forecasts, trends, outlooks, Forecasts and trends, Market trend/market analysis

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A bonanza of B-cell therapies

Article Abstract:

New treatment approaches have provided hope for patients with autoimmune diseases, especially rheumatoid arthritis and lupus. Biologic therapies targeting B-cells are found to be extremely effective and safe and scientists are researching on the role played by B-cells in autoimmunity.

Author: Gannon, Pamela
Publisher: Scientist Inc.
Publication Name: The Scientist
Subject: Biological sciences
ISSN: 0890-3670
Year: 2007
Care and treatment, B cells

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Subjects list: Health aspects, Research, Autoimmunity, Immunological research, Immunologic research
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