Retrotransposons and regulatory suites

Article Abstract:

A study discusses that retrotransposons (RTEs) may play a role in providing common regulation to a group of functions expressed during the development of oocytes and preimplantation embryos. It is found that 13% of all processed transcripts in full-grown mouse oocytes contain RTE sequences mostly from the mouse transcript family of retroviral-like elements.

United States, Oocytes, Retrotransposons

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Adding to the ends: what makes telomerase processive and how important is it?

Article Abstract:

A complex network of RNA-DNA, protein-DNA, protein-RNA, and protein-nucleotide interactions are necessary to sustain the uniquely processive property of telomerase. A better understanding would facilitate the design and search for telomerase-specific inhibitors and the development of new anti-cancer therapeutics.

Nucleic Acid Derivatives, Proteins, RNA, Nucleotides

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Cooperative interactions between epigenetic modifications and their function in the regulation of chromosome architecture

Article Abstract:

The interactions between different epigenetic mechanisms and architectural functions of epigenetic networks are discussed. A major aspect of epigenetic regulation that lies in the modification of chromosome architecture and that local changes in gene expression would be secondary consequences is proposed.

Protein binding, Chromosomes, Genetic research, Epigenetic inheritance

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