Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expression

Article Abstract:

The role of heat-shock factor 2 in cerebral cortex displays mispositioning of neurons of superficial layers. The heat-shock factor 2 affects cellular populations that assist in radial migration and directly regulates the expression of p35, a crucial actor of radial neuronal migration.

Heat shock proteins

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Expansion of adult [beta]-cell mass in response to increased metabolic demand is dependent on HNF-4[alpha]

Article Abstract:

The mutant hepatocyte nuclear factor-4[alpha] (HNF-4[alpha]) gene impairs the proliferation of pancreatic [beta]-cells in maturity-onset diabetes. These findings provide evidence that the gene is responsible for the growth of [beta] cell mass on increased metabolic demand.

Diabetes, Diabetes mellitus, Genetic aspects, Cell proliferation, Pancreatic beta cells

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Cell cycle-dependent dynamic localization of a bacterial response regulator with a novel di-guanylate cyclase output domain

Article Abstract:

A study is conducted on dynamic localization of guanylate cyclase. The results propose that local action of novel-type guanylate cyclase might constitute a general regulatory principle in bacterial growth and development.

Guanylate cyclase

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