Abstracts - faqs.org

Abstracts

Biological sciences

Search abstracts:
Abstracts » Biological sciences

Sequence-resolved detection of pausing by single RNA polymerase molecules

Article Abstract:

An ultrastable optical-trapping assay is developed to follow the motion of individual molecules of ribonucleic acid polymerase (RNAP) transcribing templates engineered with repeated sequences carrying imbedded, sequence-specific pause sites of known regulatory function. The data obtained for the lifetimes and efficiencies of pauses support a model, where the transition to pausing branches off of the normal elongation pathway and is mediated by a common elemental state, which corresponds to the ubiquitous pause.

Author: Herbert, Kristina M., Mooney, Rachel A.;. Neuman, Keir C., La Porta, Arthur, Landick, Robert; Block, Steven M., Wong, Becky J.
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Predicting gene expression from sequence

Article Abstract:

The systematic genome-wide approach to learn complex combinatorial code underlying gene expression is explained using a probabilistic approach. It is found that for successful predicting one needs a complex set of rules that use logical reasoning with motif strength as well as significant constraints and relative position.

Author: Beer, Michael A., Tavazoie, Saeed
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2004
Gene expression, Genetic research

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Regulation of RNA polymerase II transcription by sequence-specific DNA binding factors

Article Abstract:

The role of RNA polymerase II in transcription of protein-coding genes is discussed. The characterization of the sequence-specific DNA binding transcription factors is described.

Author: Kadonaga, James T.
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2004
DNA-ligand interactions, DNA binding

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Subjects list: Research, Nucleotide sequence, Base sequence, RNA polymerases
Similar abstracts:
  • Abstracts: Amino-terminal sequences of sigma-N (sigma-54) inhibit RNA polymerase isomerization. Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells
  • Abstracts: Regulation of the Neurospora circadian clock by an RNA helicase. Distinct roles for PP1 and PP2A in the Neurospora circadian clock
  • Abstracts: A simple, efficient method for the separation of humic substances and DNA from environmental samples. Arsenite-oxidizing Hydrogenobaculum strain isolated from an acid-sulfate-chloride geothermal spring in Yellowstone National Park
  • Abstracts: DNA helicases: new breeds of translocating motors and molecular pumps. Telomere maintenance requires the RAD51D recombination/repair protein
  • Abstracts: Screening, nucleotide sequence, and biochemical characterization of an esterase from Pseudomonas fluorescens with high activity towards lactones
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2025 Advameg, Inc.