Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm

Article Abstract:

Smad proteins function with synergistic and antagonistic regulators to send Dpp responses to the mesoderm for Drosophila. Integration of positive and negative regulators on enhancers of target genes seems to be a significant way for TGF-beta molecules to achieve tissue-specific induction. Dpp is in the TGF-beta superfamily and a signaling molecule.

Cellular signal transduction, Protein binding, Cell differentiation, Homeobox genes

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biniou (FoxF), a central component in a regulatory network controlling visceral mesoderm development and midgut morphogenesis in Drosophila

Article Abstract:

Results show that biniou, the Drosophila equivalent of the FoxF subfamily of forkhead domain genes, is involved in the development of visceral mesoderm and helps maintain the distinction between splanchnic and somatic mesoderm. Data indicate that the splanchnic mesoderm layers develop into musculature and other visceral organs.

United States, Physiological aspects, Musculoskeletal system, Morphogenesis

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Pyramus and thisbe: FGF genes that pattern the mesoderm of Drosophila embryos.

Article Abstract:

A study is conducted on the requirement of FGF receptors, pyramus and thisbe, for the differentiation of a variety of mesodermal tissues in the Drosophila embryo. The results reveal that the two genes exhibit dynamic patterns of expression in tissues that influence the development of different mesoderm lineages.

Science & research, Gene expression, Genetic research

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