Structure of trichamide, a cyclic peptide from the bloom-forming cyanobacterium Trichodesmium erythraeum, predicted from the genome sequence

Article Abstract:

A gene cluster for the biosynthesis of a new small cyclic peptide, dubbed trichamide, was discovered in the genome of the global, bloom-forming cyanobacterium Trichodesmium erythraeum ISM 101 because of striking similarities to the previously characterized patellamide biosynthesis cluster. Based upon detailed sequence analysis, a structure was predicted for trichamide and confirmed by Fourier transform mass spectrometry.

Nucleotide sequence, Base sequence, Cyanobacteria

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Investigation of Oscillatoria spongeliae-dominated bacterial communities in four dictyoceratid sponges

Article Abstract:

The bacterial communities of the Palauan sponges Lamellodysidea herbacea, Lamellodysidea chlorea, Lendenfeldia chondrodes, and Phyllospongia papyacea known to be dominated by Oscillatoria spongeliae is investigated. Only Lendenfeldia chondrodes, and Phyllospongia papyacea are found to contain unusual alpha-proteobacteria with insertions present in a stem-loop of their rRNA.

Environmental aspects, Marine microbiology

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Widespread occurrence and genomic context of unusually small polyketide synthase genes in microbial consortia associated with marine sponges

Article Abstract:

The diversity of polyketide synthases (PKSs) in sponge-associated microbial communities is analyzed to study the uncultured sponge bacteria. The results have proposed a simplified strategy for the targeted isolation of unusually small PKS genes from complex sponge-symbiont associations.

Bacterial genetics, Polyketides, Report

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