Structure, organization and transcriptional regulation of a family of copper radical oxidase genes in the lignin-degrading basidiomycete Phanerochaete chrysoporium

Article Abstract:

The white rot basidiomycete Phanerochaete chrysoporium generates an array of nonspecific extracellular enzymes pertaining to be involved in ligning degradation along with lignin peroxidases, mangenese peroxidases and the [H.sub.2O.sub.2]-generating copper radical oxidase, glyoxal oxidase (GLX). Preliminary analysis of the Phanerochaete chrysoporium draft genome revealed six sequences with significant similarity to GLX designated cro1 through cro6.

Physiological aspects, Genetic aspects, Genetic transcription, Transcription (Genetics), Liquid chromatography, Structure, Basidiomycota

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Tri1 in Fusarium gramenearum encodes a P450 oxygenase

Article Abstract:

The examination of an expressed sequence tag (EST) database that was derived from a variety of Fusarium graminearum expression library resulted in a putative homologue of Tri1 in F. graminearum called LH1, which was in turn analyzed using gene disrupts for determining its function. Results show that Tri1 in F. graminearum encodes a P450 oxygenase that is required for the C-8 oxygenation in F. sporotrichioides.

Fusarium

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Identification and in vivo functional analysis by gene disruption of ctnA, an activator gene involved in citrinin biosynthesis in monascus purpureus

Article Abstract:

The presence of the genes involved in CT production in the flanking regions of pksCT is investigated. It is found that the presence of an oxygenase and an oxidoreductase corresponds well to the proposed pathway of CT biosynthesis.

Biosynthesis

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