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Substitution processes in molecular evolution. I. uniform and clustered substitutions in a haploid model

Article Abstract:

A completed simulation of the mechanism of nucleotide replacements in a finite haploid population, relying in selection in a randomly varying setting, yields surprising findings. A small mutation rate estimate explains why replacements are more consistent than random for quickly varying settings and several symmetrical constructs of molecular development with quickly altering indication may show replacements that are more uniform than random because this explanation does not wholly rely on specifics of the haploid model.

Author: Gillespie, John H.
Publisher: Genetics Society of America
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1993
Research, Nucleotide sequence, Base sequence, Haploidy

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Mitochondrial DNA and Alu insertions in a genetically peculiar population: the Ayoreo Indians of Bolivia and Paraguay

Article Abstract:

A study of ninety-one Ayoreo individuals living in two Bolivian and one Paraguayan community in relation to the hypervariable 1segment of the control and eight coding regions of their mitochondrial DNA [mtDNA] is presented. The results show that the Ayoreo are differentiated in relation to their mtDNA and no equivalent differences were found with Alu insertions due to the founder effect or random loss of variability in this system.

Author: Dornelles, C. L., Battilana, J., Fagundes N. J. R., Freitas, L. B., Bonatto, S. L., Salzano, F. M.
Publisher: Wiley-Liss, Inc.
Publication Name: American Journal of Human Biology
Subject: Biological sciences
ISSN: 1042-0533
Year: 2004
Paraguay, Bolivia, Study and teaching, Mitochondrial DNA, Human biology

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Subjects list: Analysis
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