The barley Mlo gene: a novel control element of plant pathogen resistance

Article Abstract:

The broad spectrum resistance mediated by recessive host gene mutations was analyzed based on the molecular isolation of the mutation-induced recessive alleles (mlo) of barley Mlo protein. Analysis of Mlo amino acid sequence based on transposon-tagging-mediated gene isolation approach indicated the presence of six hydrophobic stretches that form six transmembrane helices. Furthermore, the Mlo protein is a member of a novel protein family that triggers a distinct mechanism for plant pathogen resistance.

Genetic aspects, Plants, Plants (Organisms), Plant-pathogen relationships, Mutation (Biology), Mutation, Barley

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Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate

Article Abstract:

Sphingosine-1-phosphate (SPP) has been shown to activate the EDG-1 and -3 subtypes of G protein-coupled receptors on endothelial cells. SPP is a novel regulator of angiogenesis. Vascular endothelial cells undergo morphogenesis into capillary networks responding to angiogenic factors.

United States, Statistical Data Included, Research, Cellular signal transduction, Neovascularization, Cytochemistry, Morphogenesis, Protein kinases, Cell receptors, Cytoskeleton, Vascular endothelium, Cell junctions

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