Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans

Article Abstract:

Dauer formation refers to the developmental arrest undergone by the L2 molt of Caenorhabditis elegans in response to adverse environmental conditions. An investigation was conducted to identify and characterize genes involved in the chemosensory transduction that controls dauer formation. Single and double mutation analysis revealed that most of the genes involved in dauer formation constitute a linear epistatic pathway. One gene, daf-11, was identified as an important regulator of the chemosensory transduction mechanism. Based on the results, a model for the function of the different dauer-formation genes is presented.

Research, Genetic regulation

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Characterization of Caenorhabditis elegans lectin-binding mutants

Article Abstract:

Forty five Caenorhabditis elegans mutants were identified using lectins from wheatgerm and soybeans. The recessive mutations spans six genes, namely srf-2, srf-3, srf-4, srf-5, srf-8 and srf-9. srf-2, -3 and -5 mutants are essentially normal except for their different lectin-binding reaction. On the other hand, the other three mutants possess various structural abnormalities in addition to aberant lectin reaction. Among these defects are aberant egg-laying, movement incoordination and abnormal morphogenesis of the copulatory bursa.

Usage, Identification and classification, Mutation (Biology), Mutation, Plant lectins

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