Toxin-antitoxin pairs in bacteria: killers or stress regulators?

Article Abstract:

The authors discuss their research on plasmid toxin-antitoxin systems which kill daughter cells. The topics of interest include the ability of Escherichia coli toxin to cleave mRNA in the ribosomal A site in order to make it function as stress regulator during amino acid starvation.

Plasmids, Bacterial cell walls, Toxins, Amino acids

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Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20

Article Abstract:

Messenger RNA elimination occurs through nonsense-mediated decay in association with the nuclear cap binding protein, CBP80. Results show that CBP80-bound mRNA undergoes a round of translation before CBP80-CBP20 are rplaced by the cytoplasmic counterpart of CBP80, elF4E.

Statistical Data Included, Protein binding, Genetic translation, Translation (Genetics)

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Computational modeling and experimental analysis of nonsense-mediated decay in yeast

Article Abstract:

Research has been conducted on nonsense-mediated decay, a conserved mRNA surveillance system. The authors describe the model developed to investigate nonsense-mediated decay process, and demonstrate that nonsense-containing transcripts can be recognized.

Eukaryotes, Yeast fungi, Yeasts (Fungi)

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