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Lactic acid permeabilizes gram-negative bacteria by disrupting the outer membrane

Article Abstract:

Lactic acid causes gram-negative bacteria to become permeable by disrupting the outer membrane. It may serve as a natural antimicrobial. It has been studied using a fluorescent-probe uptake assay and sensitization to bacteriolysis. The acid may act as a potentiator of effects of other antimicrobial substances.

Author: Alakomi, H.-L., Skytta, E., Saarela, M., Mattila-Sandholm, T., Latva-Kala, K., Helander, I.M.
Publisher: American Society for Microbiology
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2000
Finland, Foodborne diseases, Lactic acid, Bacteria, Pathogenic, Pathogenic bacteria

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Weakening effect of cell pearmeabilizers on gram-negative bacteria causing biodeterioration

Article Abstract:

An investigation and characterization of the effect of potential permeabilizers was conducted on the outer membrane (OM) properties of gram-negative bacteria causing biodeterioration. The control of growth of gram-negative bacteria provides a way to reduce biodeterioration of stone materials.

Author: Alakomi, H.-L., Saarela, M., Helander, I.M., Paananen, A., Suihko, M.-L.
Publisher: American Society for Microbiology
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2006
Science & research, All Other Basic Organic Chemical Manufacturing, Industrial Organic Chemicals, Ethylenediaminetetraacetic Acid, Analysis, Genetic aspects, Biodegradation, EDTA, Structure, Chemical properties

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The outer membrane of gram-negative bacteria inhibits antibacterial activity of brochocin-C

Article Abstract:

To determine whether the antibacterial activity of brochocin-C is equivalent to that of nisin against gram-negative bacteria, the outer membrane was studied to see whether it constitutes a barrier to brochocin-C. The effect of brochocin C on release of ATP from cells and spheroplasts of gram-negative bacteria was also considered. Brochocin-C is a broad-spectrum two-peptide bactericin produced by Brochothrix campestris ATCC 43754.

Author: Stiles, Michael E., Van Belkum, Marco J., Gao, Yan
Publisher: American Society for Microbiology
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1999
Canada, Statistical Data Included

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Subjects list: Research, Physiological aspects, Antibacterial agents, Gram-negative bacteria, Cells, Bacterial cell walls, Cell membranes, Cell permeability
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