An induction gene trap for identifying a homeoprotein-regulated locus

Article Abstract:

Homeoprotein target gene identification is a major issue in developmental biology. A strategy has been developed which is based on the nuclear addressing and internalization of exogenous homeodomains.

Europe, Genetic Engineering

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Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

Article Abstract:

Bone loss and bone remodelling are controlled by a balance the decoy receptor osteoprotegerin (OPG) and the tumour necrosis factor family molecule osteoprotegerin ligand (OPGL).

Arthritis R&D, Arthritis research

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Reprogramming neural stem cells

Article Abstract:

University researchers from Italy and NeuroSpheres, Canada, demonstrated that neural stem cells can produce B, T and myeloid cells when injected into mice.

Italy, Research and Testing Services, Neurological R&D, Brief Article, Neurological research

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