Autoimmune disease: rapid progress in our understanding of immune function promises more effective treatments for autoimmune disorders

Article Abstract:

About five percent of the population in North America and Europe are affected by autoimmune diseases.Two-third of the patients are female. There are in excess of 50 distinct diseases and syndromes which comprise autoimmune diseases.

Brief Article

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The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens

Article Abstract:

Macrophages choreograph innate immunity by phagocytosing pathogens and coordinating inflammatory responses. The ability to discriminate between different pathogens characterises the host's effective defense.

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Toll gates for pathogen selection: two classes of innate immune receptors discriminate between different microbial pathogens to mediate host deference by mammalian macrophages

Article Abstract:

Microbial pathogens in the environment produce an immediate systemic reply by all species. This reply is known as the innate immune response.

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