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Efficient enucleation of erythroblasts differentiated in vitro from hematopoietic stem and progenitor cells

Article Abstract:

A method to produce enucleated red blood cells (RBCs) efficiently in the absence of feeder cells is developed in an attempt to improve the in vitro production of RBCs from immature hematopoietic progenitor cells. The method might represent an efficient way to produce transfusable RBCs on a large scale from hematopoietic progenitors.

Author: Nakamura, Yukio, Miharada, Kenichi, Hiroyama, Takashi, Sudo, Kazuhiro, Nagasawa, Toshiro
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
United States, Methods, Protein synthesis, Protein biosynthesis, Hematopoietic stem cells, Erythrocytes, Red blood cells, Structure

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The genome sequence of the capnophilic rumen bacterium Mannheimia succiniciproducens

Article Abstract:

An isolated capnophilic Gram-negative bacterium from bovine rumen, Manheimia succiniciproducens is reported with the 2,314,078 base pair genome sequence. The metabolism of M. succiniciproducens adapts to oxygen-free rumen by using fumarate as a major electron acceptor.

Author: Sang Yup Lee, Soon Ho Hong, Sun Shim Choi, Chang Hoon Kim, Cheol Goo Hur, Jin Sik Kim, Yong Ho In, Jeong-Keun Rih, Haeyoung Jeong, Jae Jong Kim
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2004
Gram-negative bacteria, Metabolism, Genomes

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